The expertise of basic and clinical neuroscientists, along with the unique public-health system and IT infrastructure in Switzerland, should be capitalized on to create a federated system that empowers researchers from various domains to use data collected for diagnostic purposes under strict protection of privacy. This idea has already been pioneered by the MemoNet consortium, which aims to improve individuals’ diagnosis of memory dysfunction and provides a federation of clinical data across Swiss universities. We wish to expand this network to become nation-wide and to serve as a supporting and training tool for informed clinical diagnosis. A nation-wide MemoNet will increase the predictive and diagnostic power of the collected data. Finally a national brain health registry will serve an exemplary data-driven personalized medicine engine at the service of civil society.

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